Testosterone therapy shown to decrease risk of heart attacks and stroke

A Veterans Affairs database study of more than 83,000 patients found that men whose low testosterone was restored to normal had a lower risk of heart attack, stroke, or death from any cause, versus similar men who were not treated.

The study also found that men who were treated but did not attain normal levels did not see the same benefits as those whose levels reached normal levels. The study was published Aug. 6, 2015, in the European Heart Journal.

The findings run contrary to a previous controversial and much-cited VA study that was published in JAMA in 2013 This new VA study is likely to draw attention because of its larger size and longer follow-up period.

The study has a specific finding that administering the right dose is critical.  Treating low testosterone levels but not restoring them to normal levels doesn’t appear to provide much benefit particularly with regard to cardiovascular risk.